生物系統控制與醫療器材設計實驗室
Biosystem and Medical Device Design Laboratory




Contactless Object Levitation and Position Control via Multiple-Channel Airborne Ultrasonic Array
Digital-Twin Establishment in Nvidia Omniverse of Airborne Ultrasound Array Realized by Physics-Informed Neural Operators (PINO)
Professor

劉浩澧 Hao-Li Liu
教授 Ph.D., Professor
劉浩澧博士在2003年取得國立臺灣大學電機工程博士學位。於2004-2005年期間,任職於美國波士頓哈佛大學醫學院/ Brigham & Womens Hospital放射科系擔任博士後研究員,從事治療超聲醫療儀器開發。於2005-2020年間任職於長庚大學電機系、並於2020年起加入國立台灣大學生醫資訊研究所。劉浩澧博士目前繼續研究治療用超音波之醫療器材技術開發,超音波輻照對血腦屏障(BBB)開啟進行大腦藥物輸送,超音波相位陣列設計等研究議題。劉博士在治療超音波領域發表了超過 120篇之SCI論文 (包含2篇被高引用論文)、 獲得超過40件全球專利。於2011及2018年,分別獲頒臺灣科技部吳大猷先生紀念獎、科技部傑出研究獎、及科技部傑出技轉貢獻獎。在國內。陸續榮獲電機工程學會優秀青年電機工程師獎及、永信李天德基金會青年醫藥科技奬、及有庠科技發明獎。在國際,曾榮獲國際超音波學會頒發Ferderic Lizzi Award,為第一位獲頒此獎之亞洲唯一學者。
Hao-Li Liu received the Ph.D. degrees in Electrical Engineering in 2003 from the National Taiwan University, Taipei, Taiwan. The current position is the Professor, Department of Electrical Engineering, National Taiwan University. In 2004-2005, He was the research fellow of the Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA. He served as the Professor and the Director of Department of Electrical Engineering, Chang-Gung University, Taoyuan, Taiwan, and also the Adjunct Assistant Researcher of Division of Medical Engineering Research, National Health Research Institutes, Miaoli, Taiwan. Dr. Liu is currently continuing research in ultrasound thermal therapy and its treatment planning/ simulation, ultrasound-induced blood brain barrier (BBB) disruption for brain drug delivery, ultrasound phased array design. Dr. Liu has published over 130 SCI papers, over 40 worldwide patents been filed in areas of biomedical use of therapeutic ultrasound. He received the Distinguished Tech-Coop Award and the Distinguished Research Award from Chang-Gung University, respectively. Also in 2011, He received the Wu Ta-You Memorial Award from the National Science Council in Taiwan. In 2013, he received the Frederic Lizzi Award from the International Society for Therapeutic Ultrasound (ISTU) and also the Excellent Young Electrical Engineer Award from the Chinese Institute of Electrical Engineering to acknowledge his significant research contributions to therapeutic ultrasound. In 2015, as the first engineering-background honoree, Dr. Liu received the TienTe Lee Award to recognize his contribution on integrating medicine and engineering. In 2017 and 2023, he received the Academic Research Award from the Ministry of Science and Technology, Taiwan. In 2020, He joined the Department of Electrical Engineering, National Taiwan University as a professor to continue his academic carrier. Dr. Liu is a senior member of IEEE and previously served as the board member in the International Society of Therapeutic Ultrasound (ISTU) and Taiwan Association of Interventional & Therapeutic Ultrasound (TAITU). Dr. Liu funded NaviFUS Inc. in 2015, dedicated to bring neuronavigation-guided focused ultrasound method to perform transcranial CNS drug delivery and neuromodulation with an outpatient treatment fashion.
Award
2024, TECO Award, (東元科技獎)
2023, Future Technology Breakthrough Award, National Science Council of Science and Technology(未來科技突破獎).
2022-present, World’s Top 2% Scientists in lifetime (全球前2%頂尖科學家,終身科學影響力排行), Elsevier/史丹佛大學.
2021-present, World’s Top 2% Scientists in single year (全球前2%頂尖科學家,年度科學影響力排行), Elsevier/史丹佛大學.
2023, Academic Research Award, National Science Council of Science and Technology (國科會/傑出研究獎)
2022, National Innovation Award (國家新創獎)
2021, The 18th National Innovation Award (國家新創獎/「臨床新創獎」類組)
2020, Outstanding Electrical Engineering Professor Award (傑出電機工程教授獎)
2020, The 7th Y. Z. Hsu Technology Invention Award (有庠科技發明獎)
2018, Acadamic Research Award, Ministry of Science and Technology (傑出研究獎)
2017, Future Technology Breakthrough Award, Ministry of Science and Technology (未來科技突破獎)
2017, Excellent Technology Transfer Award(傑出技轉貢獻獎), Ministry of Science and Technology, Taiwan..
2015, The 12th National Innovation Award (第12屆國家新創獎/「學研新創獎」類組).
2015, TienTe Lee Award (永信李天德醫藥科技獎/青年醫藥科技奬)
2013, Excellent Young Electrical Engineer Award (優秀青年電機工程師獎)
2013, Frederick Lizzi Early Career Award, by the International Society for Therapeutic Ultrasound (ISTU; 國際治療超音波學會).
2011, Wu Ta-You Memorial Award (吳大猷先生紀念獎), National Science Council, Taiwan.
Selected Publications
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KT Chen, WY Chai, YJ Lin, CJ Lin, PY Chen, HC Tsai, CY Huang, J Kuo, HL Liu*, KC Wei*, Neuronavigation-Guided Focused Ultrasound for Transcranial Blood-Brain-Barrier Opening and Immunostimulation in Brain Tumors, Science Advances, Vol. 7, pp. 1-13, eabd0772, 2021.
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CY Lin, CH Tsai, YC Lin, CY Huang, SR Wu, CM Chen, Hao-Li Liu*, “Ultrasound-Responsive Neurotrophic Factor-Loaded Microbubble-Liposome Complex: Preclinical Investigation for Parkinson's Disease Treatment,” Journal of Controlled Release, Vol. 321, pp.519-528, 2020.
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SG Chen, CH Tsai, CJ Lin, CC Lee, HY Yu, TH Hsieh, HL Liu*, “Transcranial focused ultrasound pulsation suppresses pentylenetetrazol induced epilepsy in vivo,” Brain Stimulation, Vol. 13, pp. 35-46, 2020.
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CY Lin et al. and HL Liu*, “Ultrasound-Responsive Neurotrophic Factor-Loaded Microbubble-Liposome Complex: Preclinical Investigation for Parkinson's Disease Treatment,” Journal of Controlled Release, Vol. 321, pp.519-528, 2020.
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HL Liu et al., “Focused Ultrasound Enhances CNS Delivery of Bevacizumab for Malignant Glioma Treatment,” Radiology, Vol. 281, pp. 99-108, 2016.
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HL Liu et al., “Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain,” Proceedings of National Academy of Science USA, Vol. 107, No. 34, pp.15205-15210, 2010
More Publication: Google Scholar
Postdoctoral Researcher
朱伯駿
In vivo Epilepsy
Thi-Thuyet Truong
Ultrasound neural stimulation
Ph.D. student & Research assistant
Ph.D./ 李慧芳
.
Ph.D./ 黃聖涵
.
Ph.D./ 蔣易翰
.
M.S. student
碩四/ 陳佳文
Treatment planning/ Animal Spine
碩三/ 錢思達
Treatment planning/ Transcranial focused ultrasound
碩三/ 吳炯融
FPGA/ Ultrasound
碩三/ 蘇逸杰
FPGA/ Ultrasound system with negative feedback
碩二/ 劉東昇
.
碩二/ 黃邵陽
.
碩二/ 曾柏宇
.
碩二/ 陳孝倫
.
碩二/ 葉奕均
.
碩二/ 梁展維
.
碩二/ 蔡宜豐
.
碩二/ 羅宣融
.
碩一/ 賴宥菖
.
碩一/ 鍾昇恩
.
碩一/ 王嘉德
.
碩一/ 黃品維
.
碩一/ 吳博皓
.
碩一/ 何旻學
.
碩一/ 周孟柏
.
碩一/ 張書寧
.
.
Former member
黃士瑜
Hololens AR/ Image assisted surgery
賴正諺
Hololens AR/ Image assisted surgery
譚仕鑫
FPGA/ OCT
趙天易
Treatment planning/ Transcranial
羅敏宏
Camera AR/ Image assisted surgery
林易佑
FPGA/OCT
郭晨沅
FPGA/ Ultrasound
傅駿
Prodigy HIFU/ passive map
阮宜勁
FUS Neuromodulation for epilepsy/ fMRI in vivo /EEG in vivo
陳均懋
Driving Design for HIFU Application
甄瀟
fMRI in vivo/ MR-compatibe FUS
劉陶銘
Driving Design for HIFU Application
李丞峰
FPGA/ Ultrasound
江承祐
FPGA/ OCT
謝子涔
Prodigy HIFU/ passive map
沈欣晨
Ultrasound Depicting Space
黃琛琁
In vivo GCamp
陳品如
FPGA/ Ultrasound
陳致揚
Hololens 2 AR / medical surgery
黃梓豪
Hololens 2 AR/ Ultrasound
李永瀚
Transcranial/ Ultrasound in vivo study
譚富銘
Hololens 2 AR/ Ultrasound in medical surgery
洪國維
Deep learning/ Ultrasound
楊曼永
Ultrasound
黃芯柔
FPGA/ Ultrasound
阮唯紘
fMRI/ EEG feedback FUS treatment in epilepsy


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